What is the most commonly reported drug overdose?

Acetaminophen is the most commonly reported drug overdose because of its widespread availability and use in various over-the-counter medications. Many individuals may not realize that acetaminophen is present in numerous products, leading to accidental overdoses. The symptoms of an overdose often do not manifest immediately, which can contribute to its prevalence. Furthermore, acetaminophen has a relatively low therapeutic index, meaning that the difference between a therapeutic and a toxic dose is small. This increases the risk for individuals who may unknowingly consume excessive amounts, whether through intentional overdose or unintentional double dosing.

Given its common use in pain relief and fever reduction, many people may exceed the recommended dosage, particularly during times of illness when they might take multiple products containing acetaminophen. In contrast, while other options like ibuprofen, aspirin, and codeine can also lead to overdoses, they are less frequently reported compared to acetaminophen. Ibuprofen and aspirin, for example, have clearer dosing guidelines, and codeine misuse is often less associated with accidental overdose as it is targeted in prescription use.