Which client would likely have the least predisposition to an adverse reaction to medication?

The choice of a 9-year-old client with a skin infection represents the individual likely to have the least predisposition to an adverse reaction to medication. Children, particularly those in early developmental stages, often metabolize medications differently than adults or the elderly. Pediatric patients usually have fewer comorbidities and often better organ function, which means their bodies can process and respond to medications more efficiently in many cases.

Additionally, children typically have a lower prevalence of chronic medical conditions, such as heart disease or diabetes, that may complicate medication regimens and increase the risk of adverse reactions. The specific context of a skin infection generally involves standard treatments that are well-studied and monitored for efficacy and safety in the pediatric population.

In contrast, the elderly client with heart disease and the adult clients with diabetes and hypertension have multiple health issues and higher risks associated with polypharmacy, which can heighten the chance of drug interactions or side effects. These conditions can complicate the pharmacokinetic and pharmacodynamic processes, making medication management more complex and raising the potential for adverse reactions.